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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP4R4
All Species:
10.3
Human Site:
T758
Identified Species:
22.67
UniProt:
Q6NUP7
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NUP7
NP_066009.2
873
99452
T758
V
P
G
P
S
S
V
T
P
S
T
S
K
E
I
Chimpanzee
Pan troglodytes
XP_522937
1109
124026
T994
V
P
G
P
S
S
V
T
P
S
T
S
K
E
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_547959
916
103055
P793
T
K
T
P
T
T
L
P
K
S
I
P
I
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0Y0
875
99462
T760
V
P
G
P
S
S
S
T
A
S
T
S
K
E
I
Rat
Rattus norvegicus
NP_001128104
821
93759
L704
S
R
T
P
T
Q
S
L
S
K
N
A
A
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511225
842
94937
K726
E
K
K
R
R
D
S
K
M
A
P
S
L
V
P
Chicken
Gallus gallus
XP_421339
873
99507
C758
T
S
S
G
S
S
S
C
T
S
T
G
K
E
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696336
875
98944
S753
G
T
L
S
G
A
S
S
S
S
S
S
G
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393531
722
82259
H608
I
L
E
S
T
V
T
H
L
I
N
S
E
K
D
Nematode Worm
Caenorhab. elegans
NP_495884
986
111167
A859
S
R
L
P
L
S
S
A
A
K
E
R
D
K
L
Sea Urchin
Strong. purpuratus
XP_781974
792
88319
L678
E
A
E
E
R
A
M
L
E
I
E
R
R
N
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.1
N.A.
88.3
N.A.
90.7
83.8
N.A.
65.2
79.8
N.A.
59.2
N.A.
N.A.
31.2
23.2
40.8
Protein Similarity:
100
78
N.A.
90.5
N.A.
95
88.5
N.A.
78.4
91.1
N.A.
77.1
N.A.
N.A.
49.8
45.5
60.9
P-Site Identity:
100
100
N.A.
13.3
N.A.
86.6
6.6
N.A.
6.6
40
N.A.
13.3
N.A.
N.A.
6.6
13.3
6.6
P-Site Similarity:
100
100
N.A.
40
N.A.
86.6
20
N.A.
13.3
40
N.A.
40
N.A.
N.A.
33.3
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
19
0
10
19
10
0
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
19
% D
% Glu:
19
0
19
10
0
0
0
0
10
0
19
0
10
37
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
28
10
10
0
0
0
0
0
0
10
10
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
19
10
0
10
10
37
% I
% Lys:
0
19
10
0
0
0
0
10
10
19
0
0
37
28
0
% K
% Leu:
0
10
19
0
10
0
10
19
10
0
0
0
10
0
10
% L
% Met:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
19
0
0
10
0
% N
% Pro:
0
28
0
55
0
0
0
10
19
0
10
10
0
0
10
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
19
0
10
19
0
0
0
0
0
0
19
10
0
0
% R
% Ser:
19
10
10
19
37
46
55
10
19
55
10
55
0
10
10
% S
% Thr:
19
10
19
0
28
10
10
28
10
0
37
0
0
0
0
% T
% Val:
28
0
0
0
0
10
19
0
0
0
0
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _